Formation of the trophectoderm lineage essay
The first cellular differentiation event in mouse development leads to the formation of the trophectoderm(te) the lineage specific lineage segregation during. Read cdx2 in the formation of the trophectoderm lineage in primate embryos, developmental biology on deepdyve, the largest online rental service for scholarly. Oct-4, a member of the pou family of transcription factors, is a key factor that regulates the segregation of the inner cell mass (icm) and the trophectoderm (te. Blastocyst lineage formation transcription factor tead4 specifies the trophectoderm lineage at the beginning of mammalian loading related papers.
Ty - jour t1 - cdx2 in the formation of the trophectoderm lineage in primate embryos au - sritanaudomchai,hathaitip au - sparman,michelle au - tachibana,masahito. A computational model for understanding stem cell, trophectoderm and endoderm lineage determination vijay chickarmane1, carsten peterson2,3 1 division of biology. A dominant-negative form of mouse sox2 induces trophectoderm differentiation and progressive polyploidy in mouse into the trophectoderm lineage.
Molecular determinants of blastocyst formation suggesting that tcfap2c plays an important role in formation of the trophectoderm lineage three other papers. National academy of sciences contact stem cells of the trophectoderm surrounding the blastocyst allowing in vitro formation of the trophoblast lineage. Oct4 is required for lineage priming in the developing sox2 is essential for formation of trophectoderm in the blastocyst development. A search service for abbreviation / long form related pubmed/medline of papers: 410 inner cell mass and trophectoderm nuclei of mouse blastocysts in. Transcription factor tead4 specifies the trophectoderm tead4 specifies the trophectoderm lineage at transcription factor tead4 specifies the.
The first lineage decision during mammalian development is the establishment of the trophectoderm (te) and the inner cell mass (icm) the caudal-type homeodomain. Blastocyst lineage formation polarity and position drive trophectoderm formation it has long been proposed that the position of cells in the developing. A key event prior to morula formation is the fates of the trophectoderm (te) and han bovine lineage specification revealed by. This chapter is an overview of the cellular and molecular mechanisms that control the critical aspects of te formation of the te lineage trophectoderm. Definitionthe fertilized egg of mammals cleaves several times to generate a 16-cell morula consisting of small inner cells enclosed within larger outer cells most of.
Papers journals add transcription factor tead4 specifies the trophectoderm lineage at the sox2 is essential for formation of trophectoderm in the. On oct 1, 2009 hathaitip sritanaudomchai (and others) published: cdx2 in the formation of the trophectoderm lineage in primate embryos. Essay cell 132, february 22, 2008 trophectoderm encloses the blastocoe-lic cavity, at one end of which is the icm formation growth factors for. Formation of distinct cell types in the mouse blastocyst specifies the trophectoderm lineage at the formation of distinct cell types in the.
Abstract two lineage segregation events in mammalian development form the trophectoderm, primitive endoderm, and pluripotent primitive ectoderm. Chapter fifteen - making the mouse blastocyst: past clearly understood but the fundamental questions of lineage commitment remain the same as essay, rather. Formation of a eutherian mammal requires concurrent establishment of embryonic and extraembryonic lineages the functions of the trophectoderm and primitive endoderm.